The question of kde vs. gnome is about as popular as linux vs windows is.
having said that you can find lots of info around the net about this topic.
Some people say that using kde is a bit easier than gnome. now for some users at one point in time this may have been true but I doubt that this is still the same. other say that in kde you can do "pretty things" like run certain aps and programs, by using kde's "USE Program" option in the background selection. while in gnome you had to use a script to do the same thing and that these scripts "never seemed to work the first time"
so then its off to forums and faqs to get said application or program to work. While this might be true for some aps, its more likely a user error as opposed to a application error.
On the other hand some people say that gnome is faster than kde.
Others say that gnome is more stable and that it is easier to add themes to gnome than in kde.
Again this is a hugely popular conversation piece, maybe this will pique the interests of others to give comments about what they like/use?